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Hepatic Dose Adjustment

Look up dose adjustments for 30 drugs across Child-Pugh classes A, B, and C.

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Like Renal Dose Adjustment, this is a lookup tool covering 30 drugs, keyed to Child-Pugh class rather than a calculation. See How Calculator Tools Work for the shared layout.

How to use it

  1. Search or select a drug from the list of 30.
  2. Enter the patient's Child-Pugh class (A, B, or C) — or arrive here directly from a Child-Pugh Score result, which carries the class across automatically.

What the result shows

For the selected drug and class: the recommended dose (unchanged, reduced, or contraindicated at that severity), a note explaining why, and a monitoring recommendation specific to that drug.

Class C liver disease contraindicates a meaningful number of drugs outright — if you see a contraindication here, the next step is an alternative drug, not a smaller dose of the same one.